In a couple more days, I have a lot of stuff to say about the Palm Pre (and Sprint), but for the moment I have this to say.
The Palm Pre is the very best form factor I have ever met for a phone -- especially for hands of about the same size as mine.
It fits comfortably into the hand without a stretch, but still provides a reasonable amount of screen space. I have sometimes found myself holding it in my hand as a natural action for long periods of time.
There are a few things about the Pre that I highly appreciate, and it's perfect size is one of them.